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SysTaMatIcS 10-11-2008 09:52 PM
cancer cure discovered
 
CANCER CURE DISCOVERED?
Leukocyte InFusion 100% Effective!
Now Being Tried on Humans
(RobertsReview - 2008) Scientists are about to embark on a precedent-setting human trial to determine whether a new cancer treatment called Leukocyte InFusion Therapy (LIFT) will be as effective in humans as it has proven to be in mice.
Researchers at Wake Forest University's Baptist Medical Center will transfuse specific white blood cells, called granulocytes, from select donors, into patients with advanced cancers. A treatment using the same type cells from cancer-resistant mice has cured 100 percent of lab mice with advanced malignancies, according to Zheng Cui, Ph.D., lead researcher and associate professor of pathology.
"In mice, we've been able to eradicate even highly aggressive forms of malignancy with extremely large tumors," Cui said. "Hopefully, we will see the same results in humans. Our laboratory studies indicate that this cancer-fighting ability (of granulocytes) is even stronger in healthy humans!"
FDA-approved human trails will use white blood cells from healthy young people whose immune systems produce cells with the highest levels of cancer-fighting activity. The anti-tumor response primarily involves granulocytes of the innate human immune system, a system known for its powerful ability to fight off infections.
Granulocytes account for up to 60 percent of total white blood cells in healthy humans, researchers say, and people can donate granulocytes through a process called apheresis. It separates granulocytes and returns other blood components back to donors, whose systems quickly remanufacture replacement granulocytes.
For the study, 500 potential local donors are being recruited who are 50 years old or younger and in good health. The 100 donors with the highest cancer-killing activity in their cells will be asked to donate white blood cells for the study. Twenty-two cancer patients with solid tumors that don't respond to conventional therapies will receive the donated cells.
To find out how to participate in the trial, including how to donate granulocytes or receive the treatment, go to Wake Forest University Medical Center. Cancer-killing ability in these cells is highest during the summer, so researchers are hoping to find volunteers who can afford the therapy quickly. For additional information on how to find and participate in this and various other FDA approved trials of the newest cancer treatments, see the TrialsFinder link on this page.


Source


so could this be the end of cancer?
also the founder of the aids said that an aids vaccation will be available in 4 years! , so will this century be cancer-aids free?

SysTaMatIcS 10-13-2008 04:48 PM
Re: cancer cure discovered
 
It what promises to be one of the most watched clinical trials in history, Dr. Zheng Cui, lead researcher and Associate Professor of pathology at Wake Forest , today announced the start of clinical trials in humans, of a new experimental treatment for cancer. Dr. Cui made the announcement at "Understanding Aging: Biomedical and Bioengineering Approaches", a scientific conference sponsored by Aubrey de Grey's Methuselah Foundation. The novel treatment, Leukocyte InFusion Therapy (LIFT) was 100% effective in destroying advanced cancers in laboratory mice, according to Dr. Cui. I'll say that again in case the significance of it didn't fully register. LIFT treatments were 100% effective at curing cancer in mice with even the most advanced stages of aggressive malignant cancers. The cancer cures were affected without side effects. If the newly announced trials of LIFT in humans prove to be similarly effective at curing cancer, we may be facing the dawn of a new age in medicine.


In the precursor to these human trials, Dr. Cui, along with Dr. Mark Willingham also of Wake Forest, led a research team that found that certain mice possessed white blood cells with strong cancer fighting properties. These cells sensed the presence of cancer cells, surrounded them, and then injected them with cancer-killing compounds. This worked not only in the mice that originally possessed these cells, but also in mice to which the cells were transferred. The mice that received a transfusion of these special cancer-fighting cells had advanced cancers cured. The subject mice were also protected from new cancers when injected with what are ordinarily fatal doses of aggressive new cancers.

mr_j 10-13-2008 05:46 PM
Re: cancer cure discovered
 
we always hear about "new cures for cancer" w bil akhir the story just dies
what about the lebanese dude bi fransa that 3 years ago alo enno ektachaf el baroud, w he made a coference in lebanon w explained his treatment and he was seen as the reborn christ biwa2ta
chou sar fi halla2 ?!
I think with a bit of research we can dig up alot of stuff like that

nchallah kheir with this one bas I'm holding my excitment and judgement about it :huh:

SysTaMatIcS 10-13-2008 07:40 PM
Re: cancer cure discovered
 
wat was published back then , wasnt a " cure " for cancer , it was simply a new better treatment , and i think that its the one that doesnt cause hair loss

El-Meghwar 10-14-2008 02:57 PM
Re: cancer cure discovered
 
Just think how many doctors will lose their jobs and money if a cure for cancer was discovered.
Even if they discovered a cure they won't announce it, chemical treatments and other cancer treatments are giving them a lot of money, why would they announce a new discovered cure ? ;)

majousseh 10-14-2008 03:22 PM
Re: cancer cure discovered
 
Quote:
Originally Posted by El-Meghwar (Post 155873)
Just think how many doctors will lose their jobs and money if a cure for cancer was discovered.
Even if they discovered a cure they won't announce it, chemical treatments and other cancer treatments are giving them a lot of money, why would they announce a new discovered cure ? ;)
well,
1-doctors as humans, are as concerned as you by this disease.
2-and as humans, there are good one, and bad one. so u can't generalise.
3-there is surely "materialistic" doctors, but do you think that they are so "evil" to hide such a new presumed cure.
4-such a cure, would be a great glory to the dicoverers. be sure, they won't hide it.
5-even if the researchers are "evils and materialistics", ca you imagine how rich will they be if they sell this "invention" to the pharm industry...
6-all researchs are controlled and followed by commities, either locally in the universities, or at the national or international levels. ex. of the control: all clinical studies should be regitered on the national institute of health website. if not, it can't be published.

with all my respect.

SysTaMatIcS 10-30-2008 07:26 PM
Re: cancer cure discovered
 
What Will Happen to Patients in the Study?

Medical Tests
The following tests must be done to make sure that you are eligible for this study. Some of these tests are part of the study and generally would not be part of your routine clinical care. Depending on when you last had them, you may need to repeat some of these tests:
  • Blood tests
  • CT/MRI scan of the chest, abdomen, and pelvis
  • CT/MRI of brain
  • HIV Test
  • Pregnancy test if you are of childbearing potential
After screening tests are obtained, it is possible that based on the results, you might not be eligible to be treated on this protocol.
Many of these tests will be repeated during the study. If you participate in this study, some of these tests may be done more frequently than if you were not taking part in this research study.
Some of your blood will be sent to a research laboratory to evaluate how well your body has accepted the blood cells from your donor. The blood will be collected prior to beginning treatment on this study, immediately before and after the first white cell infusion on day+1, before the second infusion on day+2, and day+7 days or immediate after the last infusion of white cells. In addition, there will be blood draws to check how well white cells in your blood kill cancer cells in the laboratory following white cell transfusions. During the treatment period, you will have daily blood counts checked.
You will be asked to consider letting the doctors take a biopsy or fine needle aspiration of your cancer shortly after treatment begins, if it is easily accessible, such as tumors under the skin or in the superficial lymph nodes. If you agree, the biopsy will take place during the first week of your treatment. The researchers in the study will look at the tumor tissue under the microscope to see whether the white cells are surrounding the tumor. You do not have to agree to have the biopsy to participate in this treatment program.
Treatment
Treatment on this research study is an experimental and unproven way to treat cancer. This treatment uses healthy donors’ white blood cells to fight your disease. If you agree to participate, you will receive daily infusions of white cells through a line inserted into a vein in your arms, or through the central venous line if available. The number of infusions you will receive will depend on the number of white cells obtained from the donors. You will receive white cell infusion until an adequate number of cells have been infused. We predict that several donors will be required to achieve that cell dose.
The white cells transfused are also called granulocytes. They are collected from healthy blood donors at the American Red Cross using standard granulocyte collection procedures. They donors will be selected and screened by the current standards of blood donations according to the American Association of Blood Banking (AABB) and Food and Drug Administration (FDA). These donors are volunteers, and will be screened by the study team for blood donation eligibility. In addition, these donors will be tested to have reasonable cancer killing activity (CKA) in their blood as described above, compatible blood types (they will be compatible for ABO and Rh blood type with you), to pass a panel of infectious disease blood tests and to have different tissue types or the so-called human leukocyte antigens (HLA) which will lessen the chance of a serious side effect called transfusion-associated graft versus host disease (TAGVHD).
Granulocyte transfusions have been used in clinical practice for more than 30 years to treat patients who have life-threatening infections and have very low white cell count following chemotherapy. In that setting, granulocyte infusions are given to help the patients fight infections. In this clinical trial granulocyte infusions are given to hopefully help you fight cancer.
We estimate that several infusions will be needed to achieve the target cell dose. Transfusions of white cells will be administered daily. It is possible that treatment interruptions might occur, and treatment delay up to 7 days is allowed.
Donors will be asked to take dexamethasone (a steroid pill) and/or filgrastim (Neupogen) the day the before collection of cells. These two medications are widely used in clinical practice to increase the yield of white cells during collection.
White cell infusions might be administered before infectious disease marker results obtained on the day of collections from the given donor are available from the Red Cross. All donors registered to this study will be tested and screened for infectious disease markers at the time of donor registration and they will be re-tested in American Red Cross on the day of donation. Granulocytes are generally available for transfusion within approximately 24 hours after collection; at that time the infectious disease markers obtained on the day of collection are generally not yet available. Donors will have had recent (within 30 day) infectious disease markers to exclude known blood-borne diseases, and will have passed the universal donor questionnaire on the day of donation. This practice is consistent with current clinical practice, given the short life span of granulocytes. Results of these tests will become available and will be shared with you.
Your doctor may give you medications to prevent transfusion reaction, and/or to treat the reaction should it occur. Such medications may include acetaminophen (Tylenol), diphenhydramine (Benadryl) and/or hydrocortisone (a steroid).
You will be monitored closely daily with blood tests during treatment, and monthly after treatment. Your cancer will be assessed three months after the treatment is finished. You might receive other treatments for your cancer if it is getting worse during that time. If your cancer is not getting worse, you will be asked not to take other treatments for your cancer during those three months.
How Long Will I Be in the Study?
We think you will be in the study for approximately 3-5 months. The researcher or your regular doctor may decide to take you off this study if:
  • The treatment does not work in your cancer.
  • Your health gets worse.
  • Your cancer begins to grow.
You can stop participating at any time. However, if you decide to stop participating in the study, we encourage you to talk to the researcher and your regular doctor first.


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